Monday, June 21, 2004 8:15 - 9:15 Registration - 1st Floor Lobby, CoRE Building Breakfast - DIMACS Lounge, Room 401 9:15 - 9:30 Welcome and Opening Remarks Brenda Latka, DIMACS Associate Director 9:30 - 11:00 Introduction to Bacterial Transcription I Richard Ebright, Rutgers University 11:00 - 11:20 Break 11:20 - 12:50 Introduction to Bacterial Transcription II Richard Ebright, Rutgers University 12:50 - 2:00 Lunch 2:00 - 3:00 X-ray Crystallographic Insights into Bacterial Transcription: A Detailed View of the Flagellar Sigma/Anti-Sigma Complex Margareta Sorenson, (Seth Darst Group), Rockefeller University 3:00 - 3:40 Modeling Transcription Complexes Using FRET Jennifer Knight,(Ronald Levy Group), Rutgers University 3:40 - 4:00 Break 4:00 - 4:20 Molecular Simulations in Structural Biology, Macro-Molecular Assemblies Ronald Levy, Rutgers University 4:20 - 5:00 Allosteric Regulation of the lac Repressor Emilio Gallicchio, Rutgers University 5:15 Reception - 4th Floor, CoRE Building 6:00 Dinner - 4th Floor, CoRE Building Tuesday, June 22, 2004 9:00 - 9:30 Registration and Breakfast - 4th Floor, CoRE Building 9:30 - 11:00 Introduction to Eukaryotic Transcription Danny Reinberg, UMDNJ 11:00 - 11:20 Break 11:20 - 12:20 Crystallographic Studies of Protein-Protein Interactions in Transcription Regulation: CAP-RNAP and trpR Cathy Lawson, Rutgers University 12:20 - 1:40 Lunch 1:40 - 2:40 Enhancers and Insulators: Mechanism of Action Over a Distance Vasily Studitsky, UMDNJ 2:40 - 3:40 Sequence-Dependent Kinetic Model for Transcription Elongation by RNA Polymerase Lu Bai, (Michelle Wang group), Cornell University 3:40 - 4:00 Break 4:00 - 5:00 Single-Molecule Studies of Bacterial Transcription Terence Strick, Cold Spring Harbor Laboratory Wednesday, June 23, 2004 9:00 - 9:30 Registration and Breakfast - 4th Floor, CoRE Building 9:30 - 10:30 Kinetic Studies of Transcription Initiation in T7 RNA Polymerase Smita Patel, UMDNJ 10:30 - 10:50 Break 10:50 - 11:40 Kinetic Studies of Transcription Initiation by E. coli RNA Polymerase: Evidence for Conformational Changes in Open Complex Formation Ruth Saecker, University of Wisconsin 11:40 - 12:30 Role of Upstream DNA Sequences in Transcription Initiation at the Lambda PR Promoter Caroline Davis, (Tom Record Group), University of Wisconsin 12:30 - 2:00 Lunch 2:00 - 3:00 On the Role of DNA Elasticity in Transcription Regulation David Swigon, Rutgers University 3:00 - 3:45 Microscale and Macroscale Mobility of the RNAP Transcription Complex Vitaly Epshtein, NYU Medical Center 3:45 - 4:05 Break 4:05 - 4:50 The Double Ratchet Mechanism of Transcriptional Elongation Andrei Ruckenstein, Rutgers University Thursday, June 24, 2004 9:00 - 9:30 Registration and Breakfast - 4th Floor, CoRE Building 9:30 - 11:00 Regulation of Bacterial Transcription Richard Ebright, Rutgers University 11:00 - 12:45 Break - Poster Session 12:45 - 2:00 Lunch 2:00 - 3:15 Computational Detection of Cis-Regulatory Modules in the Drosophila Genome Saurabh Sinha, Rockefeller University 3:15 - 3:35 Break 3:35 - 4:35 Predictive Learning of Combinatorial Transcriptional Regulation Michael Beer, Princeton University 4:35 - 5:35 Transcriptional Regulation during Bacteriophage Development Konstantin Severinov, Rutgers University Friday, June 25, 2004 9:00 - 9:30 Registration and Breakfast - 4th Floor, CoRE Building 9:30 - 10:30 Noise in Gene Expression and Switching Anirvan Sengupta, Rutgers University 10:30 - 11:45 Transcriptional Control and Pattern Formation in the Drosophila Segmentation Gene Network Carlos Alonso and Johannes Jaeger, (John Reinitz Group) SUNY at Stony Brook 11:45 - 12:00 Epilogue Wilma Olson and Anirvan Sengupta 12:00 - 1:15 Lunch