Joachim Messing
- Rutgers University - Busch Campus
- Waksman Institute - Auditorium
- Piscataway, New Jersey
- Friday, January 20, 1995
- 4:00PM
Title of Discussion
MECHANISMS THAT LEAD TO GENETIC DIVERSITY
Abstract:
DNA sequence information provides an opportunity to
deconstruct changes that have occurred over time. Therefore, it would
be interesting to investigate the frequency, position, and sequence
context of transposition events. Within genes, it would be
interesting to investigate the impact of transposition events on mRNA
splicing and protein structure. First, we will review changes in
genetic information when and how they occur. Then, we will focus on
different recombination mechanisms and which approaches are used to
determine the chimerism of genetic information. We will select
non-linear junctions of DNA sequences to identify sequence changes
which can occur during reproduction and development of many organisms.
Out of these, changes that have been produced by the integration and
excision of transposable elements are frequently referred to as
transposable element footprints. From genomes of comparable
complexity, plant genomes are expected to have accumulated a higher
rate of footprints than mammalian genomes because of the exclusion of
somatic changes from the germline of animals.
Reception will follow lecture.
Document last modified on December 12, 1994