Title: Comparison of five new pertussis vaccination strategies
Speaker: Herbert Hethcote, University of Iowa
Date: Wednesday, May 19, 2004, 1:00 pm
Location: Hill Center, Room 260, Rutgers University, Busch Campus, Piscataway, NJ
Abstract:
Computer simulations of an age structured partial differential equations model are used to predict the impact of vaccination of children, adults and/or adolescents, and household members of newborns (cocoon strategy). Childhood vaccination greatly reduces cases in children, but increases the incidence in adolescents and adults. Routine adolescent and adult vaccination have a large direct effect, whereas the cocoon strategy has a predominantly indirect effect on young infants. The number needed to vaccinate (NNV) to prevent a case of typical pertussis in the entire population is lowest for the adolescent strategy. The cocoon strategy has the lowest NNV to prevent a case of typical pertussis in young infants.
This is joint work with Dr. Annelies Van Rie, Department of Epidemiology, University of North Carolina.
Seminar sponsored by DIMACS/BIOMAPS Seminar Series on Quantitative Biology and Epidemiology.