Presented under the auspices of the Special Focus on Computational and Mathematical Epidemiology.Co-sponsored by DIMACS and the Burroughs Wellcome Fund
Workshop Program:
Monday September 23, 2002
The Immune Response to Pathogens 8:00 - 8:40 Breakfast & Registration 8:40 - 8:45 Opening Remarks Fred Roberts, Director of DIMACS 8:45 - 8:50 Greetings by Conference Chairs: Denise Kirschner, University of Michigan Alan Perelson, Los Alamos 8:50 - 9:15 Intro to host-pathogen interactions: the host perspective Denise Kirschner, University of Michigan 9:15 - 10:10 Multiple T Cell Antigen Presenting Cell Encounters and the Role of Anergy (includes 10 minutes for discussion) Jaroslav Stark, University College London 10:10 - 11:00 Dynamics of CD8 Immune Responses (includes 10 minutes for discussion) Sergei Pilyugin, University of Florida 11:00 - 11:50 The Dynamics of Germinal Centre Selection as measured by Graph-Theoretical Analysis of Mutational Lineage Trees (includes 10 minutes for discussion) Ramit Mehr, Bar-Ilan University 12:00 - 1:45 Lunch and discussion 1:45 - 2:45 Evaluation of Human Thymic Function during Health and HIV-1 Infection (includes 10 minutes for discussion) Ping Ye, University of Michigan 2:45 - 3:45 Germinal Centers, Somatic Hypermutation and Affinity Maturation (includes 10 minutes for discussion) Steve Kleinstein, Princeton University 3:45 - 4:00 Break Contributed Talks 4:00 - 4:25 Granuloma Formation Suman Ganguli, University of Michigan 4:25 - 4:50 Modeling Yersina Pestis Bahrad Sokhansanj, Lawrence Livermore National Laboratory 5:00 - 7:00 Reception and poster sessionTuesday September 24, 2002
The Host-Viral Interaction 8:00 - 9:00 Breakfast & Registration 9:00 - 9:45 An Introduction to Modeling HIV Infection Alan Perelson, Los Alamos 9:45 - 10:30 Key factors contributing to virus load variation (includes 10 minutes for discussion) Sebastion Bonhoeffer, University of Zurich 10:30 - 11:00 Break 11:00 - 11:45 Viruses, CTL, and Cancer (includes 10 minutes for discussion) Dominick Wodarz, Fred Hutchinson Institute 11:45 - 12:30 CD4 cell turnover as a driver of HIV-1 viral phenotype switch (includes 10 minutes for discussion) Miles Davenport, University of New South Wales, Syndey 12:30 - 2:00 Lunch and discussion 2:00 - 2:45 Modeling the dynamics of T cells and TREC after treatment of HIV-1 (includes 10 minutes for discussion) Ruy Riberio, Los Alamos National Lab 2:45 - 3:30 Decline in TRECs with age and HIV infection (includes 10 minutes for discussion) Rob de Boer, Utrecht University 3:30 - 4:15 The Role of Target Cells and Specific Immunity in Primary SIV Infection (includes 10 minutes for discussion) Roland Regoes, University of Zurich 4:15 - 4:45 Break Contributed Talks 4:45 - 5:10 Modeling HIV infection with a non-mass action term Christophe Fraser, Imperial College, London, UK 5:10 - 5:35 A new model of HIV infection with time varying virus production and infected cell death rates Patrick Nelson, University of Michigan 5:35 - 6:10 Models of HIV infection in which CD4 cells are both helpers and targets Hester Korthals Altes, Hopital Pitie-Salpetriere 7:00 Workshop DinnerWednesday September 25, 2002
The Host-Bacterial Interaction 8:00 - 9:00 Breakfast & Registration 9:00 - 9:30 Introduction to host-bacterial interactions Denise Kirschner, University of Michigan 9:30 - 10:15 Cytokine subversion by B. anthracis (includes 10 minutes for discussion) Tom Kepler, Santa Fe Institute 10:15 - 11:00 Modeling the acute inflammatory response (includes 10 minutes for discussion) Carson Chow University of Pittsburgh 11:00 - 11:15 Break 11:15 - 12:00 The transmission ecology of Escherichia coli between its primary and secondary habitats (includes 10 minutes for discussion) David Gordon, Australian National University 12:00 - 12:45 The Dynamics of Granuloma Formation in the Lung (includes 10 minutes for discussion) David Gammack, University of Michigan 12:45 - 2:00 Lunch and discussion 2:00 - 3:50 The Within-Host Population Dynamics of Systemic Bacterial Infections and Their Treatment with Antibiotics (includes 10 minutes for discussion) Bruce Levin, Emory University 2:45 - 3:30 Bacterial Wall Attachment In A Flow Reactor: Mixed Culture (includes 10 minutes for discussion) Hal Smith, Arizona State University 3:30 - 4:00 General Discussion
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