DIMACS Workshop on Computational/Experimental Approaches to Protein Defects in Human Disease
April 20 - 21, 2006
DIMACS Center, CoRE Building, Rutgers University
- Organizer:
- Jean Baum, Rutgers University, baum@rutchem.rutgers.edu
- Barbara Brodsky, UMDNJ, brodsky@umdnj.edu
Presented under the auspices of the DIMACS/BioMaPS/MB Center Special Focus on Information Processing in Biology.
This special focus is jointly sponsored by
the Center for Discrete Mathematics and Theoretical Computer Science (DIMACS),
the Biological, Mathematical, and Physical Sciences Interfaces Institute for Quantitative Biology (BioMaPS),
the Rutgers Center for Molecular Biophysics and Biophysical Chemistry (MB Center), and the Division of Life
Sciences.
This workshop is jointly sponsored with Robert Wood Johnson Medical School Center for Clinical and Translational Sciences and Amicus Therapeutics.
Slides:
- Andisheh Abedini, Sylvia Tracz, and Dan Raleigh, State University of New York
Amyloid Formation by Islet Amyloid Polypeptide (Amylin) and IAPP Fragments
- Ruxandra I. Dima
Scenarios for Protein Aggregation
- Keith Dunker, Indiana University School of Medicine
Protein Intrinsic Disorder, Cell Signaling, and Alternative Splicing
- Fyodor Kondrashov, University of California
Stability and compensated pathogenic deviations
- Rohit Pappu, Washington University in St.Louis
Why Does Polyglutamine Aggregate? Insights from studies of monomers
- Shilpa Sambashivan, UCLA
Structural studies of amyloid-like fibrils
- Luis Serrano, EMBL
Sequence dependence of amyloid formation and toxicity
- Shamil Sunyaev, Brigham & Women's Hospital and Harvard Medical School
Human non-synonymous SNPs: molecular function, evolution and disease
- Ellen Solomon, King's College London School of Medicine, Guy's Hospital
Are missense variants in BRCA1 of clinical significance?
- Zhen Wang, Peng Yue, Eugene Melamud
Effect of Missense SNPs in the Framework Regions (FR) of TCR Vßs
- William Welsh, Robert Wood Johnson Medical School (UMDNJ)
Computational Method for Predicting Amyloidogenic Sequences
- Ron Wetzel, University of Tennessee
Kinetics and thermodynamics of amyloid fibril formation
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Document last modified on May 2, 2006.