DIMACS Workshop on Nucleic Acid Selection and Computing: Program

Sunday, March 15, 1998

 9:00 - 10:00   Continental Breakfast

10:00 - 11:30   Tutorial on in vitro selection
                Laura Landweber and Andrew Ellington

12:55 - 1:00    DIMACS  Welcoming Remarks

 1:00 - 1:45    Andrew Ellington, University of Texas
                "Strategies for Nucleic Acid Computing"

 1:45 - 2:30    Barry Polisky, NeXstar Pharmaceuticals Inc.
                "Therapeutic and Diagnostic Applications of 
                 SELEX-derived Aptamers"

 2:30 - 3:15     Donald Burke-Aguero, University of Colorado
                 "Simulating random recombination among functional RNAs using
                  Chimeric SELEX"

 3:15 - 3:30     Coffee break

 3:30 - 4:15     Michael Heller, Nanogen, Inc.
                 "An Integrated Microelectronic DNA Hybridization
                 System for Research, Diagnostic and Nanofabrication 
                 Applications"

 4:15 - 5:00     Pim Stemmer, Maxygen, Inc.
                 "Directed Evolution of Proteins, Pathways, Episomes and 
                 Viruses by DNA Shuffling"

 5:00 - 5:45     Robert Carlson, Molecular Sciences Institute
                 "Forced Evolution of Chemotactic Computation in E. Coli"

 5:45  - 6:30    Poster Session

 6:30            Reception,  Prospect House

Monday, March 16, 1998

 8:30 - 9:00     Continental Breakfast

 9:00 - 9:45     Mike Yarus, University of Colorado
                 "The hypothetical RNA world"

 9:45 - 10:30    Peter Unrau, Whitehead Institute, MIT
                 "RNA-catalyzed Nucleotide Synthesis"

10:30 - 10:45    Coffee break

10:45 - 11:30    Dipankar Sen, Simon Fraser University
                 "A DNA Enzyme"

11:30 - 12:00    Ron Breaker, Yale University
                 "Ribozyme and Deoxyribozyme Engineering: Creating New
                 'Molecular Hardware' for Biocomputing Applications"

12:00 - 1:30     Lunch

 1:30 - 2:15     Niles Lehman, SUNY Albany
                 "Recurrence During RNA Evolution in Vitro"

 2:15 - 3:00     Dinshaw Patel, Memorial Sloan-Kettering Cancer Center
                 "Comparative Structural Studies of RNA and DNA Aptamers"

 3:00 - 3:15     Coffee break

 3:15 - 3:35     Laura Landweber, Princeton
                 "Introduction to DNA Computers"
                 

 3:35 - 3:50     Michael Conrad, Wayne State University
                 "Building Evolutionary Friendliness into Molecular Computing"

 3:50 - 4:15     David Gifford, Douglas Melton, Julia Khodor, MIT
                 "Programmed Mutagenesis"

 4:15 - 4:30     Yuji Yamamoto and Yuzuru Husimi, Saitama University, Japan
                 "Dynamics in a 3SR evolution reactor and its applications"

 4:30 - 4:55     Mitsunori Ogihara and Animesh Ray, Rochester
                 "Evaluation of Boolean Networks by DNA"

 5:00 - 6:00     Poster Session

 6:30            Banquet,  Prospect House

Tuesday, March 17, 1998

 8:15 - 8:45     Continental Breakfast

 8:45 - 9:15     Robert Dorit, Yale
                 "In vitro evolution of complexity"

 9:15 - 9:45     John McCaskill, Jena, German
                 "DNA Evolution in Multi-Constraint Environments
                 and in vitro Evolvable Ecologies"

 9:45 - 10:15    Laura Landweber, Princeton
                 "Emergence of a Dual Catalytic RNA:  A Case for RNA
                 Preadaptation"

10:15 - 10:30    Coffee break

10:30 - 11:15    Michael Hecht, Princeton
                 "Protein evolution and design"

11:15 - 12:00    Steven Benner, University of Florida
                 "An evolutionary perspective on structure and function in
                 natural biopolymers"

12:00 - 12:30     Discussion and Conclusion of Workshop

Previous: Participation

Next: Registration

Workshop Index

DIMACS Homepage