Species evolution has long been modelled as a branching process that can uniquely be represented by a tree topology. In such a topology, each species can only be linked to its closest ancestor, while interspecies relationships such as species hybridization or lateral gene transfer in bacteria are not allowed. With the advent of phylogenetic analysis at the molecular level, there is increasing evidence that such a model is inadequate. This working group meeting is coupled with a workshop on the same subject. Its goal will be to initiate promising avenues of research designed to explore new models of "reticulate evolution" that are biologically meaningful, and computationally feasible. Attendance will be by invitation only.