- Prevalence and Associations of ARID2 Mutations in Melanoma
- Project Year:
2023
- REU Student (s):
Daniella Shomshonov | SUNY at Binghamton NY
- Student 1 Institution:
SUNY at Binghamton
- Project Mentor:
Jian Cao
- Project Mentor Area:
Rutgers Cancer Institute of New Jersey
- Project Abstract:
In this study we focused on the prevalence of ARID2 mutations in publicly available datasets and their association with known melanoma genetic features. Leveraging publicly available data from cBioPortal, we conducted comprehensive mutation analysis and statistical tests to explore the associations between ARID2 mutations and other melanoma-associated mutations, including BRAF, NF1, NRAS, KRAS, and HRAS. Our findings shed light on the potential functional significance of ARID2 mutations in melanoma biology
