Monday, August 8, 2011 6:00 - 8:00pm Reception at Panico's Restaurant 103 Church Street New Brunswick, NJ (732)545-6100 Panico's is within walking distance of the Heldrich Hotel. Here are directions Tuesday, August 9, 2011 7:45 Poster setup 8:15 - 9:00 Registration and Breakfast 9:00 - 9:30 Conference Overview Lynn Caporale 9:30 - 9:45 Special Guest: Evelyn Witkin A brief look back Session I: DNA Sequence, Structure and Replication Session Chair: Thomas Kunkel 10:00 - 10:30 Balancing eukaryotic replication asymmetry with replication fidelity Thomas Kunkel, Laboratory of Molecular Genetics and Laboratory of Structural Biology 10:30 - 11:00 DNA sequence context-dependent mutations Jan Drake, National Institute of Environmental Health Sciences 11:00 - 11:30 Break 11:30 - 12:00 Sequence-context dependence of DNA conformation Victor Zhurkin, National Cancer Institute, NIH 12:00 - 12:30 Structural Transitions in Superhelically stressed DNA Craig Benham, University of California at Davis 12:30 - 1:20 Lunch Session II: Selection for Rapid Generation of Diversity Session Chair: Richard Moxon 1:20 - 1:30 Welcoming Remarks Rebecca Wright, DIMACS Deputy Director 1:30 - 2:00 Indirect selection of local mutation rates David King, Southern Illinois University - Carbondale 2:00 - 2:30 Rapid Generation of Diversity in Bacterial Contingency Genes Richard Moxon, University of Oxford 2:30 - 3:00 Phenotypic variation due to Tandem Repeats in Mammals John "Trey" Fondon, University of Texas 3:00 - 3:30 Break 3:30 - 4:00 Determinants of repeat instability and genome evolution David Mittelman, Virginia Bioinformatics Institute 4:00 - 4:30 Adaptive Evolution via Repeated Deletions in a Vertebrate Enhancer Kathy Xie, Stanford University School of Medicine 5:00 - 5:30 Exogenes: accelerated evolution of venom peptides from cone snails and other venomous molluscs Baldomero Olivera, University of Utah 5:30 Poster session and buffet dinner Wednesday, August 10, 2011 8:30 - 9:00 Breakfast and Registration Session III: Inducible focused variation Session Chair: Nancy Maizels 9:00 - 9:30 DNA structure and regulated region-directed recombination Nancy Maizels, University of Washington 9:30 - 10:00 Balance between error-free and error-prone DNA repair in the immunoglobulin loci Patricia Gearhart, National Institute on Aging, NIH 10:00 - 10:30 Evolution of active deamination of DNA and RNA Silvestro Conticello, Core Research Laboratory, Istituto Toscano Tumori, Firenze 10:30 - 11:00 Break 11:00 - 11:30 The mechanisms underlying mutagenesis in E. coli, the p53 tumor suppressor gene, and somatic hypermutation Barbara Wright, The University of Montana 11:30 - 12:00 The three dimensional spatial organization of the Igh locus directs class switch recombination Amy Kenter, University of Illinois College of Medicine, Chicago 12:00 - 12:30 Distribution and Mechanisms of Meiotic Recombination Liisa Kauppi, Memorial Sloan-Kettering Cancer Center 12:30 - 1:30 Lunch Session IV: Genetic variation under stress and other signals Session Chair: Nancy Craig 1:30 - 2:00 Control and function of translesion DNA polymerases Graham Walker, Massachusetts Institute of Technology 2:00 - 2:30 Environmental Regulation of Switching rates in Phase Variable Pathogens and Commensal Bacteria Chris Bayliss, University of Leicester 2:30 - 3:00 DNA double-strand-breaks localize stress-induced mutagenesis in the E. coli genome Susan Rosenberg, Baylor College of Medicine 3:00 - 3:30 Break 3:30 - 4:00 Initiation of stress-induced mutagenesis and nonhomologous recombination through transcriptional RNA/DNA hybrid molecules Phil Hastings 4:00 - 4:30 Metabolite-dependent alteration of RNA folding, splicing and function Narasimhan Sudarsan, Yale University 4:30 - 5:00 Knowing where transposons go and why Nancy Craig, Johns Hopkins University School of Medicine 5:30 Poster Session and Buffet Dinner Thursday, August 11, 2011 8:30 - 9:00 Breakfast and Registration Session V: Protocols Session Chair: Laura Landweber 9:00 - 9:30 Protocols, from the Internet to the Genome John Doyle, California Institute of Technology 9:30 - 10:00 Integrons: Frameworks for information sharing Ruth Hall, The University of Sydney 10:00 - 10:30 Materials and methods in the generation of immune diversity in invertebrates L. Courtney Smith, George Washington University 10:30 - 11:00 Break 11:00 - 11:30 Generation of variation in trypanosomes David Barry, Wellcome Trust Centre for Molecular Parisitology, Glasgow, Scotland, UK 11:30 - 12:00 RNA-mediated epigenetic inheritance in Oxytricha Laura Landweber, Princeton University 12:00 - 12:30 Cryptogenes and RNA Editing Ruslan Aphasizhev, University of California, Irvine 12:30 - 1:30 Lunch Session VI: Evolution, of Genomes and Tumors Session Chair: Baldomero Olivera 1:30 - 2:00 Multiple levels of meaning in DNA sequences? and one more Ed Trifonov, University of Haifa 2:00 - 2:30 Sites of genetic instability in mitosis and cancer Ann Casper, Eastern Michigan University 2:30 - 3:00 Dissecting homologous recombination outcomes: A critical role for noncrossovers in genomic diversity Francesca Cole, Memorial Sloan-Kettering Cancer Center 3:00 - 3:30 Break 3:30 - 4:00 Transposable elements in Human Germline Genetic Variation and Cancer Kathleen H. Burns, Johns Hopkins University School of Medicine 4:00 - 4:30 Genome organization and evolution in vertebrates Giorgio Bernardi, Rome University 4:30 - 5:00 Cancer, Evolving Lawrence Loeb, University of Washington
If you would like to contribute a poster, please send title/abstract to Nicole Clark at nicolec at dimacs.rutgers.edu no later than June 1, 2011. You will be notified of acceptance of your poster as soon as possible after you submit it.