DIMACS Workshop on Identifying Genetic Signatures for the Evolution of Complex Phenotypes

June 11 - 12, 2009
DIMACS Center, CoRE Building, Rutgers University

Gyan Bhanot, Rutgers University; Cancer Institute of New Jersey and the Institute for Advanced Study, gyanbhanot at gmail.com
Raul Rabadan, Columbia University, rabadan at dbmi.columbia.edu
Presented under the auspices of the Special Focus on Computational and Mathematical Epidemiology and the DIMACS/BioMaPS/MB Center Special Focus on Information Processing in Biology.

This special focus is jointly sponsored by the Center for Discrete Mathematics and Theoretical Computer Science (DIMACS), the Biological, Mathematical, and Physical Sciences Interfaces Institute for Quantitative Biology (BioMaPS), and the Rutgers Center for Molecular Biophysics and Biophysical Chemistry (MB Center).

Workshop Program:

Thursday, June 11, 2009
 8:30 -  9:25  Registration and Breakfast	

 9:25 -  9:30  Welcome and Opening Remarks
               Gene Fiorini, DIMACS Associate Director	

 9:30 - 10:05  Uncovering Genes Associated with Autism
               Arnold J Levine, IAS, Princeton

10:05 - 10:40  Evolution of the p53 family
               Prashanth AK, IAS, Princeton

10:40 - 11:15  Human genetic variants of PP2A subunits associate with 
               altered cellular stress responses, evolutionary
               selection and cancer risk
               Alexei Vazquez, IAS, Princeton

11:15 - 11:30  Break

11:30 - 12:00  Shared genetic segments within and across populations
               Itsik Pe'er, Columbia University	

12:05 - 12:40  TBA	
               Rama Ranganathan, Southwestern Medical School

12:40 -  2:00  Lunch	

 2:00 -  2:35  Likelihood and Bayesian methods for developing detailed
	       portraits of demographic history
	       Jody Hey, Rutgers University

 2:35 -  3:10  Evolutionary origin of pairwise and higher-order
               correlations among amino acid mutations
               Alex Morozov, Rutgers University

 3:10 -  3:45  Identifying the genetic determinants of transcription factor activity
               Harmen Bussemaker, Columbia University

 3:45 -  4:00  Break

 4:00 -  4:35  Statistical Physics of Recent Human Evolution
	       Gurinder Singh Atwal, Cold Spring Harbor Labs  

 4:35 -  5:10  Alleles versus Genotypes
               Richard Neher, KITP, UCSB

 5:10 -  5:45  Lessons from another world: How genotype defines phenotype in plants
               Randall Kerstetter, the Waksman Institute

 6:30 	       Dinner	

 7:30 -  8:30  Learning to read: DNA sequencing technologies and the $1000 genome
	       Gustavo Stolovitzky, IBM Research ( dinner speech)
 8:30	       Adjourn - Buses take some participants to hotel	

Friday, June 12, 2009		

 8:45 -  9:00  Registration and Breakfast	

 9:30 - 10:05  Interactome Analysis reveals Master Regulators of human malignancy signatures	
               Andrea Califano, Columbia University

10:05 - 10:40  Mitochondrial genome haplogroup D4a is enriched in Japan semi-supercentenarians
               Masashi Tanaka, TMIG, Japan	

10:40 - 11:15  Defining the genetic complexity of phenotypic variation using segregating yeast populations 
               Ian Ehrenreich, Princeton University

11:15 - 11:30  Break	

11:30 - 12:05  Population Genomics of MicroRNA and Transcription
               Factor Binding Sites
               Kevin Chen, NYU and Rutgers University

12:05 - 12:40  Innate Immunity and RNA Viruses
	       Ben Greenbaum, IAS, Princeton	

12:40 -  2:00  Lunch	

 2:00 -  2:35  A cognitive framework for understanding cellular behavior
	       Saeed Tavazoie, Princeton University

 2:35 -  3:10  From Genotype to Phenotype: a systems viewpoint
	       Dana Pe'er, Columbia University

 3:10 -  3:25  Break

 3:25 -  4:00  Human Population Genomics: Man, Woman, Birth, Death,
               Infinity, Plus Altruism, Cheap Talks, Bad Behavior,
               Money, God and Diversity on Steroids
               Bud Mishra, NYU

 4:00 -  4:35  TBA
               Stanislas Leibler, Rockefeller University

 4:35 -  4:40  Concluding remarks
	       Raul Rabadan, Columbia University and Gyan Bhanot, Rutgers University

 4:40	       Adjourn - End of conference

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Document last modified on June 10, 2009.