DIMACS/PMMB/MBBC Workshop on DNA Topology II
April 3-4, 1997
DIMACS Center, CoRE Building, Rutgers University, Piscataway, NJ
- Organizers:
- Wilma Olson (Chair), Rutgers University, olson@rutchem.rutgers.edu
- Bernard Coleman, Rutgers University, bcoleman@stokes.rutgers.edu
- Tamar Schlick, NYU, schlick@nyu.ed
- Irwin Tobias, Rutgers University, tobias@rutchem.rutgers.edu
Presented under the auspices of the DIMACS Special Year in Mathematical Support of Molecular Biology.
Workshop Goals:
A workshop designed to reach a diverse audience of biologists-biochemists
and mathematicians-biophysicists will be held at Rutgers University in
Piscataway, New Jersey as part of its Special Year on Mathematical Support
for Molecular Biology. The Workshop is jointly sponsored by DIMACS
(The Center for Discrete Mathematics and Theoretical Computer Science at
Rutgers), PMMB (The Program on Mathematics and Molecular Biology based at
University of California, Berkeley), and MBBC (The Center for Molecular
Biophysics and Biophysical Chemistry at Rutgers). The topics of the Workshop
will include the energetics and dynamics of supercoiled and knotted DNA and
the effects of protein activity-binding and primary base sequence on DNA
structure and topology.
Specific topics include:
- use of elastic rod theory to model the structure and dynamics of DNA
- computer simulations, statistical mechanics of DNA topology
(e.g., numerical methods for visualizing and manipulating DNA topology)
- effects and/or analysis of drug, carcinogen, and protein
binding-activity on DNA structure and topology
- DNA biophysical properties (e.g., stretching, catenation)
Publication:
Biophysical Journal has agreed to publish a special issue of
refereed papers presented at the meeting. Many excellent papers dealing
with DNA Topology have appeared in the journal in the past 1-2 years.
Financial Support:
National Science Foundation support to DIMACS and PMMB is
available to cover partial travel and living expenses of interested young
scientists. For information regarding travel support please contact Sarah
Kozak, kozak@rutchem.rutgers.edu.
Logistics:
Further information on registration, accommodations, and travel is
available at the following Web site:
http://dimacs.rutgers.edu/archive/Workshops/TopologyII/index.html. Additional
queries can be sent electronically to molbiophys@rutchem.rutgers.edu.
Invited Speakers/Discussion Leaders:
- William R. Bauer (Stony Brook) Supercoiled DNA energetics/geometry
- Craig J. Benham (Mount Sinai) DNA geometry, topology, and function
- Steven M. Block (Princeton) Molecular machines; transcription against an
applied force
- Suse Broyde (NYU) Carcinogen-modified DNA conformation
- David J. Clark (NIH) Nucleosomal transcription barrier
- Bernard D. Coleman (Rutgers) Continuum mechanics; dynamics of elastic
rods; DNA topology
- Marcia O. Fenley (Continuum Dynamics) Supercoiled DNA polyelectrolyte
- Gadi Fibich (UCLA) Mathematical models of transcription regulation
- Issac Klapper (Montana State) Dynamics of elastic rods, knots, curves
- Leroy F. Liu (UMDNJ) DNA action-at-a-distance; transcription-induced
supercoiling
- Philip Nelson (Pennsylvania) Thermal fluctuations in semi-flexible polymers
- Wilma K. Olson (Rutgers) DNA conformation and topology
- Ariel Prunell (Institut J. Monod) DNA structure in nucleosomes;
minichromosomes
- Valentin Rybenkov (Berkeley) DNA catenation
- Tamar Schlick (NYU) Dynamics of superhelical DNA
- Jon Simon (Iowa) DNA knots
- Andrzej Stasiak (Lausanne) RecA-DNA complexes; DNA knots
- Irwin Tobias (Rutgers) Dynamics of elastic rods; statistical mechanics of DNA
- Alexander V. Vologodskii (NYU) Monte Carlo simulations of DNA supercoiling
- Victor B. Zhurkin (NIH) DNA structural deformations; flexibility
- Jordanka Zlatanova (Oregon State) Chromatin higher-order structure
We especially welcome presentations by new and recent Ph.D.'s, women, and
underrepresented minorities. A poster session of contributed work will be
held on April 3.
Sponsors:
DIMACS (The Center for Discrete Mathematics and Theoretical
Computer Science at Rutgers) and PMMB (The
Program on Mathematics and Molecular Biology based at Berkeley)
receive NSF support to help develop and populate
the interface between the mathematical-physical
sciences and molecular biology. MBBC (The Center
for Molecular Biophysics and Biophysical Chemistry at Rutgers),
which is funded by grants from the NIH and HHMI,
provides a focus for scholarly activities at the interface
of the biological and physical sciences at
Rutgers and coordinates a general academic program for
graduate and undergraduate students.
Biophysical Journal
"Biophysical Journal has agreed to publish a special issue of refereed
papers presented at the meeting. Many excellent papers dealing with DNA
Topology have appeared in the journal in the past 1-2 years. The
address of the journal link is:
http://www.biophysics.org/biophys/info/insttoau.htm
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Document last modified on February 11, 1997