Title: Comparison of five new pertussis vaccination strategies
Speaker: Herbert Hethcote, University of Iowa
Date: Wednesday, May 19, 2004, 1:00 pm
Location: Hill Center, Room 260, Rutgers University, Busch Campus, Piscataway, NJ
Computer simulations of an age structured partial differential equations model are used to predict the impact of vaccination of children, adults and/or adolescents, and household members of newborns (cocoon strategy). Childhood vaccination greatly reduces cases in children, but increases the incidence in adolescents and adults. Routine adolescent and adult vaccination have a large direct effect, whereas the cocoon strategy has a predominantly indirect effect on young infants. The number needed to vaccinate (NNV) to prevent a case of typical pertussis in the entire population is lowest for the adolescent strategy. The cocoon strategy has the lowest NNV to prevent a case of typical pertussis in young infants.
This is joint work with Dr. Annelies Van Rie, Department of Epidemiology, University of North Carolina.
Seminar sponsored by DIMACS/BIOMAPS Seminar Series on Quantitative Biology and Epidemiology.