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Autocorrelation Analysis in Cryo-Electron Microscopy

June 27, 2019, 3:00 PM - 3:40 PM



Rutgers University

CoRE Building

96 Frelinghuysen Road

Piscataway, NJ 08854

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Amit Singer, Princeton University

Autocorrelation analysis offers an alternative computational framework for 3-D structure determination of biological macromolecules using single particle cryo-EM. Similar to distance geometry, autocorrelation analysis also requires solving a system of low degree polynomial equations and the question of uniqueness plays a significant role.